AbYlink™
A versatile conjugation platform for antibodies
AbYlink™ is an antibody conjugation technology ideally suited for therapeutic and diagnostic applications. Thanks to AbYlink™, cytotoxic or imaging cargos can be selectively attached to the Fc portion of any IgG without prior modification of the antibody. This technology preserves the original affinity of the antibody to its target.

Our value proposition
To provide a solution to biotech or pharma partners to generate rapidly a proprietary antibody drug conjugates or imaging antibody. Our technology is compatible with any human IgG as well as with bispecifc antibodies and protein-Fc fusions.
Our proprietary conjugation technology AbYlink™ can be accessed on a target or antibody-specific basis.
As a first step, we welcome the opportunity to showcase the advantages of our proprietary AbYlink™ platform under a joint Proof-of-Concept study.

Key features
- Defined, reproducible and invariable conjugation with no impact on antigen-binding regions
- Homogenous antibody conjugation
- Conjugation process completed in less than 1 hour
- Non enzymatic conjugation process
- No prior antibody purification or modification necessary
- Compatible with most linker technologies for Antibody Drug conjugations
- Compatible with most imaging agents for use as PET, SPECT and fluorescent tracers
- Compatible with all IgG formats
- GMP-compatible technology
Press Releases
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April 24, 2025
Debiopharm and Oncodesign Services Launch Strategic Collaboration to Propel Radiopharmaceuticals in Preclinical Research
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April 22, 2025
Debiopharm to Reveal Insights from their ADC, DDR Inhibitor, and Antibody Conjugation Technology Research at The 2025 AACR Conference in…
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September 21, 2023
Debiopharm and SunRock Biopharma Partner to Advance Antibody Drug Conjugates for Hard-to-Treat Cancers
Publications
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December 14, 2024
Site-selective template-directed synthesis of antibody Fc conjugates with concomitant ligand release
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September 7, 2022
AbYlink™: A template mediated regio-selective labeling method for preclinical imaging of therapeutic antibodies
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February 18, 2022
Template directed synthesis of antibody Fc conjugates with concomitant ligand release